Pharmacovigilance is in charge of studying all the activities related to the detection, evaluation, understanding and prevention of medicines, its purpose is focused on maintaining a beneficial relationship in favor of patients in the use of medicines from their authorization to their exit from the market. Therefore, its implementation in the health system is of vital importance1 . In Colombia there is a Pharmacovigilance program in the hands of the National Institute for Food and Drug Surveillance (INVIMA), which requires the task of monitoring the drugs marketed in the territory to determine the safety of their use. An important part of this process is the notification of adverse events produced by medications, which must be reported, any citizen can do it, but especially the institutions that provide health services. This investigation carries out an evaluation in the Zayma S.A.S Clinic of the city of Montería about the implementation of the pharmacovigilance program, through the HENRI scale instrument, provided by INVIMA. The preliminary findings allowed us to show a low level of implementation of the program, Therefore, an intervention was carried out in the sense of giving talks and training that would improve the degree of implementation of the program, to later evaluate if the intervention improved its implementation status using the same instrument, achieving evidence of a considerable increase in its qualification and a state of implementation in progress, which allows to provide a higher quality service