Publicación:
Evaluación del uso de antimicrobianos en la unidad de cuidados intensivos adultos de una clínica en la ciudad de Montería

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dc.audience
dc.contributor.advisorHiltony Stanley, Villa Dangond
dc.contributor.advisorLopez De La Espriella, Eva María
dc.contributor.authorGresy Isabel, Guerra Madrid
dc.contributor.authorEdwin Antonio, Hoyos Rivero
dc.contributor.authorMaría Alejandra, Jaramillo Arrieta
dc.contributor.authorLaura Milena, Oquendo Ortega
dc.contributor.authorAndry Yulieth, Torres Blanco
dc.contributor.juryErnesto, Fuentes Fabra
dc.contributor.juryRoger David, Espinosa
dc.date.accessioned2024-08-14T21:15:03Z
dc.date.available2024-08-14T21:15:03Z
dc.date.issued2024-08-14
dc.description.abstractLa evaluación del uso de antimicrobianos en la Unidad de Cuidados Intensivos (UCI) de una clínica en Montería identificó prácticas de prescripción y resistencia que representan un desafío significativo para el manejo de infecciones en pacientes críticos. El objetivo del estudio fue evaluar el cumplimiento de las guías institucionales, identificar infecciones por gérmenes resistentes, evaluar el uso de antimicrobianos a través de la dosis diaria definida (DDD) y socializar los resultados con el personal asistencial. Se llevó a cabo un análisis retrospectivo de 26 pacientes, examinando sus perfiles demográficos y clínicos, las prescripciones de antimicrobianos y la adherencia a las guías de tratamiento. Los resultados mostraron una predominancia de mujeres (64.29%) y condiciones prevalentes como hipertensión (26.9%) y diabetes tipo 2 (23.1%). Se detectó una alta incidencia de shock séptico (30.8%) y neumonía adquirida en la comunidad (19.2%). Los microorganismos más comunes fueron E. coli y Klebsiella pneumoniae, con una resistencia significativa a betalactamasas de espectro extendido (BLEE) y carbapenémicos en el 13.79% de los casos. La evaluación mostró una adherencia moderada a las guías de tratamiento, con variabilidad en la duración de los tratamientos y ajustes basados en resultados microbiológicos. La supervisión por parte de infectólogos fue frecuente, pero insuficiente en algunos casos, lo que sugiere áreas de mejora. Las conclusiones indican la necesidad de una mayor adherencia a los protocolos de tratamiento, educación continua del personal y vigilancia constante de la resistencia antimicrobiana para mejorar los resultados clínicos en la UCI.spa
dc.description.abstractThe evaluation of antimicrobial use in the Intensive Care Unit (ICU) of a clinic in Montería identified prescription practices and resistance that pose a significant challenge for infection management in critically ill patients. The study aimed to assess guideline adherence, identify infections by resistant germs, evaluate antimicrobial use through the defined daily dose (DDD), and share results with the healthcare staff. A retrospective analysis of 26 patients was conducted, examining their demographic and clinical profiles, antimicrobial prescriptions, and guideline adherence. Results showed a predominance of women (64.29%) and prevalent conditions such as hypertension (26.9%) and type 2 diabetes (23.1%). There was a high incidence of septic shock (30.8%) and community-acquired pneumonia (19.2%). The most common microorganisms were E. coli and Klebsiella pneumoniae, with significant resistance to extended-spectrum beta-lactamases (ESBL) and carbapenems in 13.79% of cases. The evaluation revealed moderate adherence to treatment guidelines, with variability in treatment duration and adjustments based on microbiological results. Supervision by infectious disease specialists was common but insufficient in some cases, suggesting areas for improvement. Conclusions indicate the need for greater adherence to treatment protocols, continuous staff education, and constant surveillance of antimicrobial resistance to improve clinical outcomes in the ICU.eng
dc.description.degreelevelPregrado
dc.description.degreenameTecnólogo(a) en Regencia de Farmacia
dc.description.modalityPráctica Empresarial
dc.description.tableofcontentsRESUMENspa
dc.description.tableofcontentsABSTRACTspa
dc.description.tableofcontents1. INTRODUCCIÓN ………………………………..11spa
dc.description.tableofcontents2. MARCO REFERENCIAL………………………….13spa
dc.description.tableofcontents2.1 MARCO DE ANTECEDENTES…………………....13spa
dc.description.tableofcontents2.2 MARCO CONCEPTUAL…………………………15spa
dc.description.tableofcontents2.3 MARCO TEÓRICO…………………………….18spa
dc.description.tableofcontents2.4 MARCO LEGAL……………………………………..23spa
dc.description.tableofcontents3. OBJETIVOS……………………………...25spa
dc.description.tableofcontents3.1 OBJETIVO GENERAL…………………………..25spa
dc.description.tableofcontents4. DISEÑO METODOLÓGICO…………………26spa
dc.description.tableofcontents4.1 ENFOQUE Y TIPO DE INVESTIGACIÓN………..26spa
dc.description.tableofcontents4.2 ESCENARIO DE ESTUDIO………………………..26spa
dc.description.tableofcontents4.3 UNIDAD DE ANÁLISIS………………...26spa
dc.description.tableofcontents4.4 PRINCIPIOS DE INCLUSIÓN Y EXCLUSIÓN………………...26spa
dc.description.tableofcontents4.5 POBLACIÓN, TIPO DE MUESTREO Y CÁLCULO DEL TAMAÑO DE LA MUESTRA ……………………………………………………………………………..27spa
dc.description.tableofcontents4.6 MÉTODOS E INSTRUMENTOS DE RECOLECCIÓN DE DATOS……….…..27spa
dc.description.tableofcontents4.7 ANÁLISIS DE DATOS…………………………28spa
dc.description.tableofcontents5. RESULTADOS Y DISCUSIÓN………………..29spa
dc.description.tableofcontents5.1 RESULTADOS……………29spa
dc.description.tableofcontents5.2 DISCUSIÓN DE RESULTADOS…………....45spa
dc.description.tableofcontents6. CONCLUSIONES………………49spa
dc.description.tableofcontents7. RECOMENDACIONES………………………………...51spa
dc.description.tableofcontents8. REFERENCIAS BIBLIOGRÁFICAS………………………….52spa
dc.description.tableofcontents9. ANEXOS……………………60spa
dc.identifier.instnameUniversidad de Córdoba
dc.identifier.reponameRepositorio Institucional Unicórdoba
dc.identifier.repourlhttps://repositorio.unicordoba.edu.co
dc.identifier.urihttps://repositorio.unicordoba.edu.co/handle/ucordoba/8526
dc.language.isospa
dc.publisherUniversidad de Córdoba
dc.publisher.facultyFacultad de Ciencias de la Salud
dc.publisher.placeMontería, Córdoba, Colombia
dc.publisher.programTecnología en Regencia de Farmacia
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dc.rightsCopyright Universidad de Córdoba, 2024
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2
dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.keywordsantimicrobials
dc.subject.keywordsICU
dc.subject.keywordsBacterial resistance
dc.subject.keywordsGuideline adherence
dc.subject.keywordsNosocomial infection
dc.subject.proposalAntimicrobianos
dc.subject.proposalUCI
dc.subject.proposalResistencia bacteriana
dc.subject.proposalCumplimiento de guías
dc.subject.proposalInfección nosocomial
dc.titleEvaluación del uso de antimicrobianos en la unidad de cuidados intensivos adultos de una clínica en la ciudad de Montería
dc.typeTrabajo de grado - Pregrado
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1f
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.contentText
dc.type.driverinfo:eu-repo/semantics/bachelorThesis
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dspace.entity.typePublication
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