Publicación:
The effects of Plasmodium vivax gestational malaria on the clinical and immune status of pregnant women in Northwestern Colombia

Vista sencilla de ítem
dc.contributor.authorYASNOT, MARÍAspa
dc.contributor.authorPERKINS, DOUGLASspa
dc.contributor.authorCORREDOR, MAURICIOspa
dc.contributor.authorYANOW, STEPHANIEspa
dc.contributor.authorCARMONA, JAIMEspa
dc.contributor.authorMAESTRE, AMANDAspa
dc.date.accessioned2018-03-05T16:19:03Zspa
dc.date.available2018-03-05T16:19:03Zspa
dc.date.issued2013-09-30spa
dc.description.abstractObjetive: The study explored the effects of Plasmodium vivax infection on the balance of pro- versus anti- inflammatory cytokines and chemokines and their relationship with some clinical and epidemiology outcomes. Methods: Thirty-five pregnant women were recruited. Of these, 15 subjects had malaria at delivery (GM+), and 20 had no exposition to infection throughout the pregnancy (GM-) and at delivery. Epidemiological and clinical data were recorded after reviewing the clinical records. At delivery, whole blood from the mother as well as placental tissue was collected. Diagnosis of infection was performed by thick smear and a polymerase chain reaction (PCR). Expression of pro-inflammatory and anti-inflammatory cytokines and chemokines was measured by a real time PCR. Results: The clinical and epidemiological variables explored were similar in both groups, with the exception of gestational age. When comparing the GM+ group with the GM- group, it is clear that although the differences generally are not significant, pro- inflammatory cytokines are elevated in both maternal blood and placental; anti-inflammatory ones are elevated in the mother and reduced in the placenta, and the chemokines are reduced in both compartments, except for MCP-1 which is elevated in all. Conclusion: The results appear to be strongly affected by the small number of women with GM by P. vivax at childbirth. Additional studies are needed with larger groups in this and other regions of the country.spa
dc.identifier.citationYasnot MF, Perkins DJ, Corredor M, Yanow S, Carmona-Fonseca J, Maestre A. The Effects of Plasmodium vivax Gestational Malaria on the Clinical and Immune Status of Pregnant Women in Northwestern Colombia. Colomb Med. 2013; 44(3):172-7.spa
dc.identifier.urihttps://repositorio.unicordoba.edu.co/handle/ucordoba/583spa
dc.language.isoengspa
dc.rightsCopyright Universidad de Córdoba, 2020spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución 4.0 Internacional (CC BY 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/spa
dc.subjectPlasmodium vivax, malaria, pregnancy, placenta, cytokine, chemokine, Colombiaspa
dc.titleThe effects of Plasmodium vivax gestational malaria on the clinical and immune status of pregnant women in Northwestern Colombiaspa
dc.title.alternativeEfectos de la malaria gestacional por Plasmodium vivax sobre el estado clínico e inmune en gestantes del Noroccidente de Colombia.eng
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dspace.entity.typePublication
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
The effects of Plasmodium vivax gestational malaria on the clinical and immune status of pregnant women in Northwestern Colombia.pdf
Tamaño:
354.49 KB
Formato:
Adobe Portable Document Format
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
H.A.I Artículos