Publicación:
Análisis descriptivo y predictivo de geohelmintiasis en niños escolares de Tierralta, Córdoba, Colombia

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dc.contributor.advisorYasnot Acosta, María Fernandaspa
dc.contributor.authorNisperuza Vidal, Ana Karina
dc.date.accessioned2023-02-27T22:12:33Z
dc.date.available2023-02-27T22:12:33Z
dc.date.issued2023-02-27
dc.description.abstractLas geohelmintiasis son parasitosis intestinales ocasionadas por los macropárasitos Ascaris lumbricoides, Trichuris trichiura, Necator americanus y Ancylostoma duodenale. En Colombia constituyen un problema de salud pública y el departamento de Córdoba se encuentra en una de las regiones con mayor prevalencia de estas infecciones. Se realizó un estudio descriptivo y predictivo para la evaluación de geohelmintiasis en 70 niños de la Institución Educativa Santa Fé de Ralito, observándose una prevalencia de parasitosis del 55.7%, siendo Trichuris el parásito de mayor frecuencia (92%). El estudio inmunológico evidenció un perfil de supresión de la respuesta anti inflamatoria con predominio de IP-10 y TGF-β. Se diseñó un modelo predictivo de infección por geohelmintiasis con un buen desempeño (exactitud: 0.714) como piloto de herramientas para la prevención de estas patologías a nivel comunitario y rural.spa
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagíster en Microbiología Tropicalspa
dc.description.modalityTrabajos de Investigación y/o Extensiónspa
dc.description.tableofcontents1. INTRODUCCIÓN .......................................................................................................... 9spa
dc.description.tableofcontents2. OBJETIVOS ................................................................................................................. 11spa
dc.description.tableofcontents2.1 Objetivo general ......................................................................................................... 11spa
dc.description.tableofcontents2.2 Objetivos Específicos ................................................................................................. 11spa
dc.description.tableofcontents3. MARCO TEORICO ..................................................................................................... 12spa
dc.description.tableofcontents3.1 Parásitos Geohelmintos .............................................................................................. 12spa
dc.description.tableofcontents3.1.1 Ascaris lumbricoides ...................................................................................... 12spa
dc.description.tableofcontents3.1.2 Trichuris trichiura .......................................................................................... 14spa
dc.description.tableofcontents3.1.3 Uncinarias. ...................................................................................................... 16spa
dc.description.tableofcontents3.2 Epidemiología ........................................................................................................ 17spa
dc.description.tableofcontents3.3 Características clínicas de la infección por geohelmintos. .................................... 18spa
dc.description.tableofcontents3.4 Impacto de las infecciones por Geohelmintos en la población infantil ................. 20spa
dc.description.tableofcontents3.5 Inteligencia Artificial en salud. .............................................................................. 21spa
dc.description.tableofcontents4. MATERIALES Y METODOS ..................................................................................... 23spa
dc.description.tableofcontents4.1 Tipo de estudio. .......................................................................................................... 23spa
dc.description.tableofcontents4.2 Población y criterios de Elegibilidad .......................................................................... 23spa
dc.description.tableofcontents4.3 Recolección de datos .................................................................................................. 23spa
dc.description.tableofcontents4.4 Toma de muestras ....................................................................................................... 23spa
dc.description.tableofcontents4.5 Diagnóstico parasitológico de la geohelmintiasis ...................................................... 24spa
dc.description.tableofcontents4.6 Conteo de eosinófilos, basófilos y determinación de hemoglobina ........................... 25spa
dc.description.tableofcontents4.7 Detección de Citoquinas ........................................................................................ 25spa
dc.description.tableofcontents4.8 Análisis estadístico descriptivo .................................................................................. 28spa
dc.description.tableofcontents4.9 Relaciones y comparaciones entre grupos .................................................................. 28spa
dc.description.tableofcontents4.10 Modelo Predictivo ................................................................................................... 28spa
dc.description.tableofcontents4.10.1 Conjunto de datos .............................................................................................. 29spa
dc.description.tableofcontents4.10.2 Preprocesamiento............................................................................................... 30spa
dc.description.tableofcontents4.10.3 Entrenamiento y evaluación del modelo ........................................................... 30spa
dc.description.tableofcontents4.11 Aspectos éticos. ........................................................................................................ 32spa
dc.description.tableofcontents5. RESULTADOS ............................................................................................................ 33spa
dc.description.tableofcontents5.1 ANALISIS DESCRIPTIVO ....................................................................................... 33spa
dc.description.tableofcontents5.1.1 Variables demográficas ....................................................................................... 33spa
dc.description.tableofcontents5.1.2 Variables epidemiológicas ................................................................................... 34spa
dc.description.tableofcontents5.1.3 Variables Clínicas ................................................................................................ 35spa
dc.description.tableofcontents5.2 RELACIONES Y COMPARACIONES ENTRE GRUPOS...................................... 37spa
dc.description.tableofcontents5.2.1 Variables demográficas ...................................................................................... 37spa
dc.description.tableofcontents5.2.2 Variables epidemiológicas ................................................................................... 37spa
dc.description.tableofcontents5.2.3 Variables Clínicas ................................................................................................ 37spa
dc.description.tableofcontents5.3 ANALISIS PREDICTIVO .................................................................................... 40spa
dc.description.tableofcontents5.3.1 Pre-procesamiento del conjunto de datos ....................................................... 40spa
dc.description.tableofcontents5.3.2 Entrenamiento y Evaluación ........................................................................... 42spa
dc.description.tableofcontents5.3.3 Influencia en la Predicción ............................................................................. 43spa
dc.description.tableofcontents6. DISCUSION ................................................................................................................. 44spa
dc.description.tableofcontents7. CONCLUSIONES ........................................................................................................ 53spa
dc.description.tableofcontents8. LIMITACIONES Y PROSPECTIVAS ........................ 54spa
dc.format.mimetypeapplication/pdfspa
dc.identifier.urihttps://repositorio.unicordoba.edu.co/handle/ucordoba/7243
dc.language.isospaspa
dc.publisherGrupo de Investigaciones Microbiológicas y Biomédicas de Córdoba, GIMBICspa
dc.publisherUniversidad de Córdobaspa
dc.publisherNew York Universityspa
dc.publisher.facultyFacultad de Medicina Veterinaria y Zootecniaspa
dc.publisher.placeMontería, Córdoba, Colombiaspa
dc.publisher.programMaestría en Microbiología Tropicalspa
dc.rightsCopyright Universidad de Córdoba, 2023spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.subject.keywordsSoil-transmitted helmintheng
dc.subject.keywordsAscariseng
dc.subject.keywordsTrichuriseng
dc.subject.keywordsTierraltaeng
dc.subject.keywordsCórdobaeng
dc.subject.keywordsImmune responseeng
dc.subject.keywordsTH2eng
dc.subject.keywordsPredictive modeleng
dc.subject.proposalGeohelmintosspa
dc.subject.proposalAscarisspa
dc.subject.proposalTrichurisspa
dc.subject.proposalTierraltaspa
dc.subject.proposalCórdobaspa
dc.subject.proposalRespuesta inmunespa
dc.subject.proposalTH2spa
dc.subject.proposalModelo predictivospa
dc.titleAnálisis descriptivo y predictivo de geohelmintiasis en niños escolares de Tierralta, Córdoba, Colombiaspa
dc.typeTrabajo de grado - Maestríaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/masterThesisspa
dc.type.redcolhttps://purl.org/redcol/resource_type/TMspa
dc.type.versioninfo:eu-repo/semantics/submittedVersionspa
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