Publicación:
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study)

dc.contributor.authorGagliardi B, Rosaspa
dc.contributor.authorMartínez A, Dianaspa
dc.contributor.authorTellechea H, Beatrizspa
dc.contributor.authorSitjar Q, Pedrospa
dc.contributor.authorLlambí D, Silviaspa
dc.contributor.authorArruga L, Maríaspa
dc.date.accessioned2015-01-07 00:00:00
dc.date.accessioned2022-06-17T20:08:35Z
dc.date.available2015-01-07 00:00:00
dc.date.available2022-06-17T20:08:35Z
dc.date.issued2015-01-07
dc.format.mimetypeapplication/pdfspa
dc.identifier.doi10.21897/rmvz.78
dc.identifier.eissn1909-0544
dc.identifier.issn0122-0268
dc.identifier.urihttps://repositorio.unicordoba.edu.co/handle/ucordoba/5290
dc.identifier.urlhttps://doi.org/10.21897/rmvz.78
dc.language.isospaspa
dc.publisherUniversidad de Córdobaspa
dc.relation.bitstreamhttps://revistamvz.unicordoba.edu.co/article/download/78/147
dc.relation.citationeditionNúm. 1 , Año 2015 : Revista MVZ Córdoba Volumen 20(1) Enero-Abril 2015spa
dc.relation.citationendpage4487
dc.relation.citationissue1spa
dc.relation.citationstartpage4482
dc.relation.citationvolume20spa
dc.relation.ispartofjournalRevista MVZ Córdobaspa
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dc.relation.referencesGramer I, Leidolf R, , DÓ§ring B, Klintzsch S, Krämer E-M, Yalcin E, Petzinger E, Geyer J. Breed distribution of the nt230 (del4) MDR1 mutation in dogs. Vet J 2011; 189 (1):67-71. http://dx.doi.org/10.1016/j.tvjl.2010.06.012spa
dc.relation.referencesGeyer J, Klintzsch S, Meerkamp K, Wöhlke A, Distl O, Moritz A, Petzinger E . Detection of the nt230 (del4) MDR1 mutation in White Swiss Shepherd dogs: case reports of doramectin toxicosis, breed predisposition, and microsatellite analysis. J Vet Pharmacol Therap 2007; 30 (5):482-485. http://dx.doi.org/10.1111/j.1365-2885.2007.00885.xspa
dc.relation.referencesRoulet A, Puel O, Gesta S, Lepage J-F, Drag M, Soll M, Alvinerie M, Pineau T. MDR1-deficient genotype in Collie dog hypersensitive to the Pglycoprotein substrate ivermectin. European J of Pharmacol 2003; 460 (2-3):85-91. http://dx.doi.org/10.1016/S0014-2999(02)02955-2spa
dc.relation.referencesMealey KL, Bentjen SA, Gay JM, Canthor GH. Ivermectin sensitivity in collies is associated with a deletion mutation of the MDR1 gene. Pharmacogenetics 2001; 11 (8):727-733. http://dx.doi.org/10.1097/00008571-200111000-00012spa
dc.relation.referencesFraga J, Rodríguez J, Fuentes O, Castex M, Fernández-Calienes A. Comparación entre 5 métodos para la extracción de ADN de triatomíneos: su utilización en la técnica de ADN polimórfico amplificado al azar Rev Cubana Med Trop 2004; 56 (3):208-13.spa
dc.relation.referencesMealey KL. Farmacogenetica. Clin Vet NA Med Peq Anim 2006; 36 (5):961-973.spa
dc.relation.referencesNeff MW, Robertson KR, Wong AK, Safra N, Broman KW, Slatkin M, Mealey KL, Pedersen NC. Breed distribution and history of canine mdr1-1Δ a pharmacogenetic mutation that marks the emergence of breed from the collie lineage. Proc Nat Acad Sci 2004; 101 (32):11725-11730. http://dx.doi.org/10.1073/pnas.0402374101spa
dc.relation.referencesBissonnette S, Paradis M, Daneau I, Silverside DW. The ABCB1-1Δ mutation is not responsible for subchronic neurotoxicity seen in dogs of noncollie breeds following macrocyclic lactone treatment for generalized demodicosis. Vet Dermatol 2008; 20(1):60-66. http://dx.doi.org/10.1111/j.1365-3164.2008.00731.xspa
dc.relation.referencesGeyer J, DÓ§ring B, Godoy JR, Leidolf R, Moritz A, Petzinger E. Frecuency of the nt230 (del4) MDR1 mutation in Collies and related dog breeds in Germany. J Vet Pharmacol Therap 2005; 28 (6):545-551. http://dx.doi.org/10.1111/j.1365-2885.2005.00692.xspa
dc.relation.referencesGagliardi R, García C, Llambí S, Arruga MV. Analysis of mdr1-1Δ mutation of MDR1 gene in the "Cimarron Uruguayo" dog. Rev MVZ Córdoba 2013; 18(2):3480-3483.spa
dc.relation.referencesGagliardi R. Estudios geneticos en caninos de raza Cimarron Uruguayo (Canis familiaris). [Tesis de Maestría]. Montevideo: Universidad de la República, Programa de Desarrollo de las Ciencias Básicas (PEDEClBA); 2009.spa
dc.relation.referencesTomiyasu H, Goto-Koshino Y, Fujino Y, Ohno K, Tsujimoto H. Epigenetic regulation of the ABCB1 gene in drug-sensitive and drug-resistant lymphoid tumour cell lines obtained from canine patients. Vet J 2014; 199 (1): 103-109. http://dx.doi.org/10.1016/j.tvjl.2013.10.022spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourcehttps://revistamvz.unicordoba.edu.co/article/view/78spa
dc.subjectDogsspa
dc.subjectivermectinespa
dc.subjectP-glycoproteinspa
dc.titleThe search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study)spa
dc.title.translatedThe search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study)eng
dc.typeArtículo de revistaspa
dc.typeJournal articleeng
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTREFspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dspace.entity.typePublication
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