Infections associated with health care have generated great economic problems because they are a cause of over-costs in health institutions and in turn in the Colombian health system. The objective of the study is to collect and analyze information to find out which IAAS at the surgical site generate the greatest impact of cost overruns in health institutions in Colombia in the last five years. For this study, documents were used as reference population, including 4 books, 3 databases such as Embase, Science Direct, Proquest, 39 articles, 9 journals, 10 consulted reports and web records of official sites that deal with cost overruns. generated by infections associated with health care, from the surgical site in health institutions in Colombia in the last five years, a total of 57 documents were used to nurture and build this work.